Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057175 | 0.89 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9056961 | 0.89 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8034224 | 0.85 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8799682 | 0.84 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9057402 | 0.84 | PARP1 (0.38) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8556101 | 0.84 | GRIN2D (0.39) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8036162 | 0.81 | CHEK1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8559119 | 0.81 | CHEK1 (0.46) | — | |
| SCHEMBL8557905 | 0.78 | GRIN2D (0.43) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8557418 | 0.78 | PDE5A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783506-A1 | NEW HETEROCYCLIC SUBSTITUTED IMIDAZOLOQUINOXALINONES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010572-A1 | NEW HETEROCYCLIC SUBSTITUTED IMIDAZOLOQUINOXALINONES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | disclosed |