Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,1,2,2-Tetrachloroethane SCHEMBL11501345 | 0.95 | TDP1 (0.50) | ALDH1A1TDP1TSHRLMNA | |
| 1,1,2,2-Tetrachloroethane SCHEMBL4452716 | 0.82 | — | — | |
| Chloroform SCHEMBL1194194 | 0.82 | — | — | |
| Chloroform SCHEMBL11347367 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRLMNA | |
| 1,1,2,2-Tetrachloroethane SCHEMBL8872399 | 0.74 | TDP1 (1.00) | ALDH1A1TDP1TSHRLMNA | |
| 1,1,2,2-Tetrachloroethane SCHEMBL2564 | 0.74 | — | — | |
| 1,2-Dichloroethane SCHEMBL127 | 0.74 | — | — | |
| 1,2-Dichloroethane SCHEMBL4584447 | 0.74 | — | — | |
| 1,2-Dichloroethane SCHEMBL5324114 | 0.74 | — | — | |
| 1,2-Dichloroethane SCHEMBL6233635 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783496-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996005186-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |