Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799903 | 1.00 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8800551 | 0.87 | ALOX5 (0.77) | ALOX5 | |
| SCHEMBL8965247 | 0.87 | ALOX5 (0.77) | ALOX5 | |
| SCHEMBL13447681 | 0.80 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL2626920 | 0.80 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL25992812 | 0.80 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL8800680 | 0.78 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL8801130 | 0.78 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL8799899 | 0.78 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL8965059 | 0.78 | ALOX5 (0.64) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | claimed |
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |