Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800823 | 0.90 | CYSLTR1 (0.48) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8801970 | 0.84 | CYSLTR1 (0.58) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8143321 | 0.84 | CYSLTR1 (0.53) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8801669 | 0.83 | CYSLTR1 (0.54) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8139258 | 0.80 | CYSLTR1 (0.53) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8802992 | 0.80 | CYSLTR1 (0.54) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8801178 | 0.80 | GPBAR1 (0.51) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL12559634 | 0.78 | BRD4 (0.51) | — | |
| SCHEMBL8802493 | 0.78 | CYSLTR1 (0.52) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8801917 | 0.76 | CYSLTR1 (0.54) | CYSLTR1GPBAR1ALOX5CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799826-A1 | Heteroaryl substituted phenylene derivatives, their preparation and their use as leukotriene receptor antagonists | KOWA CO. LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |