Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801508 | 0.90 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL8800538 | 0.83 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL8802992 | 0.81 | CYSLTR1 (0.54) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL8801917 | 0.81 | CYSLTR1 (0.54) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL8801610 | 0.80 | MAOA (0.56) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL8801512 | 0.77 | CYSLTR1 (0.53) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089132 | 0.77 | CYSLTR1 (0.62) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL8801120 | 0.76 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089807 | 0.76 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6088435 | 0.76 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799826-A1 | Heteroaryl substituted phenylene derivatives, their preparation and their use as leukotriene receptor antagonists | KOWA CO. LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |