Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083970 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7083950 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7090558 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1MAPK11MAPK14MAPK13 | |
| SCHEMBL7084129 | 0.79 | PTGS2 (0.68) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7087758 | 0.79 | PTGS2 (0.68) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7085196 | 0.76 | PTGS2 (0.59) | PTGS2PTGS1MAPK11MAPK14MAPK13 | |
| SCHEMBL7089166 | 0.76 | PTGS2 (0.61) | PTGS2PTGS1MAPK11MAPK14MAPK13 | |
| SCHEMBL7085197 | 0.75 | PTGS2 (0.75) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7089059 | 0.74 | PTGS2 (0.65) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 | |
| SCHEMBL8802036 | 0.74 | PTGS2 (0.65) | PTGS2PTGS1MAPK11MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |