Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL30575190 | 0.79 | L3MBTL1 (0.46) | L3MBTL1TDP1KMT2ATP53ALOX15 | |
| Methyl Alcohol SCHEMBL28731737 | 0.79 | L3MBTL1 (0.46) | L3MBTL1TDP1KMT2ATP53ALOX15 | |
| SCHEMBL38507 | 0.79 | L3MBTL1 (0.45) | L3MBTL1TDP1KMT2ATP53HPGD | |
| SCHEMBL28257547 | 0.79 | L3MBTL1 (0.45) | L3MBTL1TDP1KMT2ATP53HPGD | |
| SCHEMBL9630701 | 0.78 | L3MBTL1 (0.45) | L3MBTL1TDP1KMT2ATP53ALOX15 | |
| SCHEMBL28829681 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TDP1KMT2ATP53HPGD | |
| Bicarbonate SCHEMBL28887905 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TDP1KMT2ATP53HPGD | |
| Calcium SCHEMBL31344979 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TDP1KMT2ATP53HPGD | |
| SCHEMBL30027079 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TDP1KMT2ATP53HPGD | |
| SCHEMBL28872294 | 0.77 | L3MBTL1 (0.44) | L3MBTL1TDP1KMT2ATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731803-A4 | NOVEL FURANODIAZEPINES | MERCK & CO INC (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0731803-A1 | NOVEL FURANODIAZEPINES | MERCK & CO. INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5453424-A | Furanodiazepines | MERCK & CO., INC. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1995014695-A1 | NOVEL FURANODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |