Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800505 | 0.93 | LMNA (0.37) | CYP19A1KMT2ALMNACYP2C9ATP6V1B2 | |
| SCHEMBL8800987 | 0.92 | KMT2A (0.45) | CYP19A1KMT2ALMNACYP2C9ATP6V1B2 | |
| SCHEMBL8801716 | 0.91 | LMNA (0.37) | CYP19A1KMT2ALMNACYP2C9ATP6V1B2 | |
| SCHEMBL8802048 | 0.85 | LMNA (0.42) | CYP19A1KMT2ALMNAHDAC1HDAC6 | |
| SCHEMBL8801785 | 0.84 | LMNA (0.37) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8800501 | 0.84 | LMNA (0.44) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8801651 | 0.79 | CYP19A1 (0.37) | CYP19A1KMT2ALMNAHDAC1HDAC6 | |
| SCHEMBL8803110 | 0.79 | LMNA (0.37) | CYP19A1KMT2ALMNACYP2C9ATP6V1B2 | |
| SCHEMBL8801047 | 0.78 | LMNA (0.46) | KMT2ALMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL9058127 | 0.78 | HDAC1 (0.37) | CYP19A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |