Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849702 | 0.92 | PTH1R (0.48) | PTH1R | |
| SCHEMBL849704 | 0.92 | PTH1R (0.48) | PTH1R | |
| SCHEMBL849703 | 0.92 | PTH1R (0.48) | PTH1R | |
| SCHEMBL847522 | 0.88 | PTH1R (0.69) | PTH1RMAPT | |
| SCHEMBL16104852 | 0.87 | PTH1R (0.52) | PTH1RMAPT | |
| SCHEMBL880096 | 0.86 | PTH1R (0.38) | PTH1RMMP1MMP2MMP3MMP9 | |
| SCHEMBL10291123 | 0.82 | PTH1R (0.59) | PTH1R | |
| SCHEMBL848638 | 0.82 | PTH1R (0.71) | PTH1R | |
| SCHEMBL847496 | 0.82 | PTH1R (0.57) | PTH1RMMP2MMP3 | |
| SCHEMBL16302341 | 0.81 | PTH1R (0.52) | PTH1RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |