Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802032 | 0.93 | NPSR1 (0.42) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL9415867 | 0.91 | DHODH (0.44) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL9415889 | 0.84 | DHODH (0.43) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL9058577 | 0.83 | CYP19A1 (0.37) | ALDH1A1CYP19A1 | |
| SCHEMBL9415881 | 0.82 | DHODH (0.41) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL9058575 | 0.82 | CYP19A1 (0.39) | ALDH1A1CYP19A1 | |
| SCHEMBL10372641 | 0.82 | DHODH (0.54) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL10372640 | 0.82 | DHODH (0.54) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL9415882 | 0.82 | DHODH (0.44) | DHODHNPSR1HPGDL3MBTL1MAPT | |
| SCHEMBL10374437 | 0.81 | DHODH (0.55) | DHODHNPSR1HPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |