Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | AGT | P01019 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801196 | 0.95 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8801132 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL8801633 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8802225 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8802507 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8801640 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8801076 | 0.81 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL8801125 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL8802257 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8801542 | 0.79 | AGTR1 (0.48) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680480-B1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY | LUSO FARMACO INST (IT) | 1997-07-30 | — | — | EP | disclosed |
| EP-0680480-A1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY. | LUSO FARMACO INST (IT) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017067-A1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1994-08-04 | — | — | WO | disclosed |