Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.52 |
| ▸ | SCD | O00767 | 2/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087414 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1SCDFADS1SMN1; SMN2 | |
| SCHEMBL7083972 | 0.81 | PTGS2 (0.75) | PTGS2PTGS1SMN1; SMN2ALDH1A1ALOX5 | |
| SCHEMBL7085282 | 0.76 | PTGS2 (0.46) | PTGS2PTGS1SMN1; SMN2ALDH1A1ALOX5 | |
| SCHEMBL9206986 | 0.75 | PTGS2 (0.73) | PTGS2PTGS1SCDFADS1 | |
| SCHEMBL7780772 | 0.75 | PTGS2 (0.51) | PTGS2PTGS1SCDFADS1 | |
| SCHEMBL8796975 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1SCDFADS1 | |
| SCHEMBL7085206 | 0.74 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL7981803 | 0.74 | PTGS2 (0.53) | PTGS2SCDFADS1MAPK11MAPK14 | |
| SCHEMBL7780441 | 0.72 | PTGS2 (0.46) | PTGS2PTGS1SCDFADS1 | |
| SCHEMBL27627173 | 0.72 | PTGS2 (0.49) | PTGS2PTGS1SMN1; SMN2ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |