Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511854 | 0.83 | SLC22A6 (0.63) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL594038 | 0.83 | SLC22A6 (0.63) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL12543813 | 0.83 | HTR1A (0.43) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL30733595 | 0.83 | HTR1A (0.50) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL7495860 | 0.83 | BCHE (0.60) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL29938170 | 0.83 | BCHE (0.60) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL2312464 | 0.81 | RHEB (0.49) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL29966634 | 0.81 | HTR1A (0.52) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL9871925 | 0.80 | RHEB (0.51) | HTR1BHTR1ACYP1A2CYP3A4LMNA | |
| SCHEMBL8583050 | 0.79 | SLC22A6 (0.46) | HTR1BHTR1ACYP1A2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525584-B1 | 6-Oxo-azepinoindole derivatives, process and intermediates for their preparation and medicaments containing them | SOLVAY PHARM GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0525584-A1 | 6-Oxo-azepinoindole derivatives, process and intermediates for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |