Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.47 |
| ▸ | GAK | O14976 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803113 | 0.76 | PDGFRB (0.60) | PDGFRBPDGFRACYP2A6GAKCYP2E1 | |
| SCHEMBL4353296 | 0.75 | PDGFRB (0.68) | PDGFRBPDGFRACYP2A6GAKCYP2E1 | |
| SCHEMBL8801931 | 0.74 | PDGFRB (0.61) | PDGFRBPDGFRACYP2A6GAK | |
| SCHEMBL17715688 | 0.71 | PDGFRB (0.55) | PDGFRBPDGFRACYP2A6GAKCYP2E1 | |
| SCHEMBL862480 | 0.71 | CCR1 (0.72) | CYP2A6 | |
| SCHEMBL8803053 | 0.71 | PDGFRB (0.51) | PDGFRBPDGFRACYP2A6 | |
| SCHEMBL31060603 | 0.70 | PDGFRB (1.00) | PDGFRBPDGFRACYP2A6GAK | |
| SCHEMBL8501282 | 0.70 | PDGFRB (1.00) | PDGFRBPDGFRACYP2A6GAK | |
| SCHEMBL31060213 | 0.69 | PDGFRB (1.00) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 | |
| SCHEMBL19180724 | 0.68 | PDGFRB (1.00) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584222-B1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE POULENC RORER INT (US) | 1997-10-08 | — | — | EP | claimed |