Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692747 | 0.83 | NPSR1 (0.39) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7849939 | 0.83 | NPSR1 (0.39) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9088057 | 0.81 | MAPT (0.35) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9088063 | 0.81 | MAPT (0.35) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10441067 | 0.80 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL2095792 | 0.80 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10441066 | 0.80 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7173250 | 0.79 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6216053 | 0.79 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL12131055 | 0.79 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |
| WO-1996002539-A1 | SUBSTITUTED TRIAZOLYL METHYL PHENYL NAPHTHYRIDONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |