Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088057 | 1.00 | MAPT (0.35) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL5780531 | 0.89 | — | — | |
| SCHEMBL5780529 | 0.89 | — | — | |
| SCHEMBL5780538 | 0.89 | — | — | |
| SCHEMBL2095792 | 0.88 | NPSR1 (0.34) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL10441067 | 0.88 | NPSR1 (0.34) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL10441066 | 0.88 | NPSR1 (0.34) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL8110602 | 0.82 | NPSR1 (0.37) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL8110600 | 0.82 | NPSR1 (0.37) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL8801560 | 0.81 | NPSR1 (0.39) | MAPTNPSR1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0544981-A2 | Naphthyridone carboxylic acid derivatives and antibacterial compositions containing them | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |