Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802526 | 0.82 | HDAC4 (0.46) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL12786103 | 0.76 | HDAC4 (0.53) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL4983834 | 0.75 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL13878120 | 0.74 | HDAC4 (0.50) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL8399182 | 0.73 | HDAC4 (0.44) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL12299163 | 0.73 | HDAC4 (0.49) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL24687854 | 0.71 | HDAC4 (0.47) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL1006801 | 0.71 | HDAC4 (0.62) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL11317482 | 0.70 | HDAC4 (0.50) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL12299148 | 0.69 | HDAC4 (0.45) | HDAC4HDAC2HDAC8USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751767-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0751767-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-01-08 | — | — | EP | disclosed |