Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388243 | 0.86 | TSHR (0.54) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL14019802 | 0.76 | TSHR (0.54) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL8389128 | 0.75 | FABP4 (0.56) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL8180699 | 0.75 | TSHR (0.60) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL8390306 | 0.74 | MAPT (0.52) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL17625298 | 0.73 | F10 (0.58) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL3388130 | 0.73 | MAPT (0.76) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2214591 | 0.72 | GAA (0.50) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL12804727 | 0.72 | HDAC6 (0.60) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL8390463 | 0.72 | TSHR (0.47) | TSHRALDH1A1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |