Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | AGT | P01019 | 2/20 | 0.42 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272146 | 0.94 | AGTR1 (0.41) | AGTR1AGTR2AGTACHE | |
| SCHEMBL8801166 | 0.89 | AGTR1 (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL8801182 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2AGTACHE | |
| SCHEMBL8801784 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL8802257 | 0.84 | AGTR1 (0.46) | AGTR1AGTR2AGTSLC33A1 | |
| SCHEMBL8802507 | 0.84 | AGTR1 (0.46) | AGTR1AGTR2AGTSLC33A1 | |
| SCHEMBL8802490 | 0.83 | AGTR1 (0.45) | AGTR1AGTR2AGTSLC33A1ACHE | |
| SCHEMBL9270321 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2AGTACHE | |
| SCHEMBL9389995 | 0.82 | AGTR1 (0.46) | AGTR1AGTR2AGTSLC33A1 | |
| SCHEMBL8801692 | 0.82 | SLC33A1 (0.38) | AGTR1SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680480-B1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY | LUSO FARMACO INST (IT) | 1997-07-30 | — | — | EP | disclosed |