Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610667 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL7608350 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL7608326 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7608719 | 0.92 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7615492 | 0.92 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9182746 | 0.90 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL8803776 | 0.90 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL8330927 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL6217934 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL8329739 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523512-B1 | 8-vinyl- and 8-ethinyl-quinolone carboxylic acids | BAYER AG (DE) | 1997-01-15 | — | — | EP | claimed |
| EP-0523512-A1 | 8-vinyl- and 8-ethinyl-quinolone carboxylic acids | BAYER AG (DE) | 1993-01-20 | — | — | EP | claimed |
| EP-0523512-B1 | 8-vinyl- and 8-ethinyl-quinolone carboxylic acids | BAYER AG (DE) | 1997-01-15 | — | — | EP | disclosed |
| EP-0523512-A1 | 8-vinyl- and 8-ethinyl-quinolone carboxylic acids | BAYER AG (DE) | 1993-01-20 | — | — | EP | disclosed |