Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444433 | 0.96 | CYP2C19 (0.40) | CYP2C19MEN1KMT2AHPGDTSHR | |
| SCHEMBL8803348 | 0.86 | KMT2A (0.38) | MEN1KMT2AHPGDTSHRHSD17B10 | |
| SCHEMBL8443916 | 0.84 | KMT2A (0.37) | MEN1KMT2AHPGDTSHRHSD17B10 | |
| SCHEMBL8444338 | 0.81 | MEN1 (0.36) | CYP2C19MEN1KMT2AHPGDTSHR | |
| SCHEMBL8442687 | 0.80 | CYP2C19 (0.50) | CYP2C19MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8440455 | 0.79 | TNKS (0.50) | CYP2C19MEN1KMT2ATSHRKDM4E | |
| SCHEMBL8802443 | 0.79 | HTR2B (0.56) | CYP2C19 | |
| SCHEMBL5175529 | 0.75 | HDAC8 (0.62) | ALDH1A1HDAC8 | |
| Hydrochloric Acid SCHEMBL8705323 | 0.74 | HDAC8 (0.60) | ALDH1A1HDAC8 | |
| Hydrochloric Acid SCHEMBL8699835 | 0.73 | DHODH (0.50) | MEN1KMT2AHPGDRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |