Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 14/20 | 0.53 |
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803291 | 1.00 | TBXAS1 (0.54) | TBXAS1TBXA2RPTGIRPPARGPPARA | |
| SCHEMBL8803111 | 0.98 | TBXAS1 (0.55) | TBXAS1TBXA2RPTGIRPPARGPPARA | |
| SCHEMBL8803341 | 0.94 | TBXAS1 (0.54) | TBXAS1TBXA2RPTGIR | |
| SCHEMBL8804598 | 0.94 | TBXAS1 (0.54) | TBXAS1TBXA2RPTGIR | |
| SCHEMBL8805695 | 0.87 | TBXAS1 (0.56) | TBXAS1TBXA2R | |
| SCHEMBL8805691 | 0.87 | TBXAS1 (0.56) | TBXAS1TBXA2R | |
| SCHEMBL8802756 | 0.85 | TBXAS1 (0.55) | TBXAS1TBXA2RPPARGPPARA | |
| SCHEMBL9529664 | 0.83 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL5429073 | 0.83 | TBXAS1 (0.52) | TBXAS1TBXA2R | |
| SCHEMBL5429070 | 0.83 | TBXAS1 (0.52) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |