Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803115 | 0.89 | MAOB (0.65) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8805057 | 0.86 | MAOB (0.69) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8803219 | 0.85 | MAOB (0.63) | MAOBMAOASIGMAR1TSHRACHE | |
| Hydrochloric Acid SCHEMBL8804469 | 0.84 | MAOB (0.62) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8803135 | 0.84 | SIGMAR1 (0.67) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8804647 | 0.84 | MAOB (0.64) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8803225 | 0.83 | MAOB (0.58) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8804925 | 0.82 | MAOB (0.71) | MAOBMAOASIGMAR1ACHEDCUN1D1 | |
| SCHEMBL8805081 | 0.82 | MAOB (0.64) | MAOBMAOASIGMAR1TSHRACHE | |
| SCHEMBL8804959 | 0.82 | MAOB (0.59) | MAOBMAOASIGMAR1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |