Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639724 | 0.91 | MAPT (0.44) | MAPTKMT2AMEN1POLBTSHR | |
| SCHEMBL8803577 | 0.81 | KMT2A (0.47) | MAPTKMT2AMEN1POLBTSHR | |
| SCHEMBL6645645 | 0.77 | MAPT (0.43) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL6642418 | 0.77 | KMT2A (0.43) | MAPTKMT2AMEN1POLBTSHR | |
| SCHEMBL8803583 | 0.72 | KMT2A (0.46) | MAPTKMT2AMEN1POLBTSHR | |
| SCHEMBL6640576 | 0.72 | KMT2A (0.41) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6643025 | 0.70 | KMT2A (0.39) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL12324775 | 0.69 | CHRM2 (0.46) | MAPTHTT | |
| SCHEMBL9135817 | 0.68 | POLB (0.69) | MAPTKMT2AMEN1POLBTSHR | |
| SCHEMBL6639732 | 0.68 | KMT2A (0.45) | MAPTKMT2AMEN1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |