Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639732 | 0.84 | KMT2A (0.45) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL6639724 | 0.75 | MAPT (0.44) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL6642424 | 0.74 | KMT2A (0.44) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL6645642 | 0.74 | MAPT (0.43) | KMT2AMEN1MAPTALDH1A1THRB | |
| SCHEMBL8803569 | 0.72 | MAPT (0.43) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL8803577 | 0.69 | KMT2A (0.47) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL9135817 | 0.68 | POLB (0.69) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL6640574 | 0.67 | KMT2A (0.40) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL4179176 | 0.66 | KMT2A (0.60) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL6646929 | 0.66 | GAA (0.52) | KMT2AMEN1POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |