Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 12/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804835 | 0.93 | MAOB (0.58) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8803570 | 0.92 | MAOB (0.60) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8804123 | 0.89 | KDM4E (0.56) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8803826 | 0.87 | MAOB (0.57) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8807258 | 0.87 | KDM4E (0.53) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8803881 | 0.87 | MAOB (0.55) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8802406 | 0.87 | MAOB (0.52) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8806310 | 0.86 | KDM4E (0.56) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8804641 | 0.86 | MAOB (0.55) | CCR3MAOBMAOAKDM4ETDP1 | |
| SCHEMBL8804348 | 0.86 | MAOB (0.45) | CCR3MAOBMAOAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |