Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | CCR3 | P51677 | 8/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806310 | 0.93 | KDM4E (0.56) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8803570 | 0.91 | MAOB (0.60) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8805525 | 0.89 | MAOB (0.58) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8803826 | 0.89 | MAOB (0.57) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8805081 | 0.89 | MAOB (0.64) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8805921 | 0.88 | MAOB (0.56) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8805057 | 0.87 | MAOB (0.69) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8804647 | 0.87 | MAOB (0.64) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8803597 | 0.87 | CCR3 (0.53) | KDM4ETDP1MAOBMAOACCR3 | |
| SCHEMBL8805138 | 0.86 | MAOB (0.51) | KDM4ETDP1MAOBMAOACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |