Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 18/20 | 0.61 |
| ▸ | CCKBR | P32239 | 18/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807834 | 0.93 | CCKAR (0.58) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8805668 | 0.91 | CCKAR (0.52) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8806083 | 0.89 | CCKAR (0.58) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8803760 | 0.88 | CCKAR (0.62) | CCKARCCKBR | |
| SCHEMBL8803627 | 0.87 | CCKAR (0.51) | CCKARCCKBR | |
| SCHEMBL8803748 | 0.84 | CCKAR (0.55) | CCKARCCKBR | |
| SCHEMBL8804278 | 0.84 | CCKAR (0.60) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8803465 | 0.83 | ALDH1A1 (0.50) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8806922 | 0.82 | CCKAR (0.52) | CCKARCCKBR | |
| SCHEMBL8805076 | 0.82 | CCKAR (0.57) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755384-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028391-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |