SCHEMBL8804102

SCHEMBL8804102

N#Cc1ccc(OP(O)(=S)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.46
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
IL18 Q14116 1/20 0.39
MAOA P21397 1/20 0.39
ABCB1 P08183 1/20 0.38
HPGD P15428 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
F2 P00734 2/20 0.38
HTT P42858 1/20 0.38
SLC6A4 P31645 1/20 0.38
MMP2 P08253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8804107 0.84 MAOB (0.47) MAOBTSHRMEN1RAB9AKMT2A
SCHEMBL7743966 0.84 MAOB (0.47) MAOBTSHRMEN1RAB9AKMT2A
SCHEMBL408021 0.81 SRC (0.54) TSHRMEN1KMT2AKDM4ELMNA
SCHEMBL2354339 0.80 CA2 (0.43) MAOBMEN1RAB9AKMT2AKDM4E
SCHEMBL10021620 0.79 MAOB (0.42) MAOBTSHRKDM4ELMNAPKM
SCHEMBL21815469 0.77 TDP1 (0.66) MAOBTSHRMEN1RAB9AKMT2A
SCHEMBL28383839 0.77 MAOB (0.47) MAOBTSHRMEN1RAB9AKMT2A
Cyanofenphos SCHEMBL119236 0.75 MAOB (0.43) MAOBTSHRLMNAMAPK1HTT
Cyanophos SCHEMBL3361537 0.73 MAOB (0.44) MAOBTSHRRAB9ALMNAMAPT
SCHEMBL28460825 0.73 MAOB (0.50) MAOBTSHRMEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537957-B1 Fungicidal silicon-containing compounds, their preparation and their agrochemical and medicinal uses SANKYO CO (JP) 1997-02-12 EP disclosed
EP-0431968-B1 Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents SANKYO CO (JP) 1995-03-15 EP disclosed
EP-0332387-B1 Triazole derivatives, their preparation and their use as fungicides SANKYO CO (JP) 1993-11-24 EP disclosed
EP-0537957-A1 Fungicidal silicon-containing compounds, their preparation and their agrochemical and medicinal uses Sankyo Company Limited (JP) 1993-04-21 EP disclosed