Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806070 | 0.91 | ABCC1 (0.51) | MAOBMAOAABCC1ACHEKMT2A | |
| SCHEMBL8804158 | 0.90 | MAOB (0.54) | MAOBMAOAACHEKMT2AGAA | |
| SCHEMBL8805523 | 0.88 | DCUN1D1 (0.43) | MAOBMAOALMNAALDH1A1 | |
| SCHEMBL8805548 | 0.84 | UBE2M (0.39) | MAOBMAOAKMT2AGAAL3MBTL1 | |
| SCHEMBL8805456 | 0.82 | KMT2A (0.61) | MAOBMAOAKMT2ALMNAMEN1 | |
| SCHEMBL8804783 | 0.82 | KMT2A (0.61) | MAOBMAOAKMT2ALMNAMEN1 | |
| SCHEMBL8803651 | 0.82 | KMT2A (0.61) | MAOBMAOAKMT2ALMNAMEN1 | |
| SCHEMBL8803907 | 0.82 | KMT2A (0.61) | MAOBMAOAKMT2ALMNAMEN1 | |
| SCHEMBL8806034 | 0.81 | KMT2A (0.59) | MAOBMAOAKMT2ALMNAMEN1 | |
| SCHEMBL8804874 | 0.81 | MAOB (0.49) | MAOBMAOAACHEKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |