Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123555 | 0.78 | CA2 (0.46) | CA2CA1PTPN11EPHX1MAPK1 | |
| SCHEMBL22004000 | 0.72 | CA1 (0.40) | CA2CA1PTPN11EPHX1 | |
| SCHEMBL228558 | 0.71 | CA2 (0.50) | CA2CA1PTPN11EPHX1MAPK1 | |
| SCHEMBL28936404 | 0.70 | CA1 (0.39) | CA2CA1PTPN11EPHX1F2 | |
| SCHEMBL21629339 | 0.69 | CA2 (0.48) | CA2CA1PTPN11EPHX1CA7 | |
| SCHEMBL21831901 | 0.69 | CA2 (0.48) | CA2CA1PTPN11EPHX1CA7 | |
| SCHEMBL20725006 | 0.69 | CA2 (0.48) | CA2CA1PTPN11EPHX1CA7 | |
| SCHEMBL28529581 | 0.69 | CA2 (0.48) | CA2CA1PTPN11EPHX1CA7 | |
| SCHEMBL17292686 | 0.69 | CA2 (0.48) | CA2CA1PTPN11EPHX1CA7 | |
| SCHEMBL20723413 | 0.69 | CA2 (0.48) | CA2CA1PTPN11EPHX1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070173-C | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1158606-A | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |