Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | TOP1 | P11387 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801262 | 0.95 | LMNA (0.57) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801930 | 0.95 | LMNA (0.57) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8804235 | 0.91 | LMNA (0.51) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801864 | 0.88 | LMNA (0.52) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801932 | 0.86 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801859 | 0.86 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801266 | 0.86 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8802764 | 0.84 | CYP3A4 (0.45) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8801369 | 0.84 | LMNA (0.51) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8802753 | 0.84 | MEN1 (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |