Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.57 |
| ▸ | PTGIR | P43119 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802766 | 0.93 | PTGDR2 (0.53) | PTGDR2PTGIRPPARAPPARGFFAR1 | |
| SCHEMBL8803298 | 0.89 | PTGDR2 (0.60) | PTGDR2PTGIRPPARAPPARGHPGD | |
| SCHEMBL8358846 | 0.86 | PPARA (0.60) | PPARAPPARGHPGDHDAC3HDAC1 | |
| SCHEMBL8356709 | 0.86 | TACR1 (0.55) | PTGDR2PTGIRPPARAPPARGHPGD | |
| SCHEMBL8356625 | 0.85 | PTGIR (0.56) | PTGDR2PTGIRPPARAPPARGFFAR1 | |
| SCHEMBL8356604 | 0.83 | PTGIR (0.60) | PTGDR2PTGIRPPARAPPARGHPGD | |
| SCHEMBL8802863 | 0.82 | PTGIR (0.53) | PTGDR2PTGIRPPARAPPARG | |
| SCHEMBL8804548 | 0.82 | PTGDR2 (0.57) | PTGDR2PTGIRPPARAPPARGHPGD | |
| SCHEMBL8803787 | 0.79 | PTGIR (0.63) | PTGDR2PTGIRPPARAPPARG | |
| SCHEMBL8803652 | 0.79 | PPARA (0.57) | PTGDR2PTGIRPPARAPPARGHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |