Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804559 | 0.93 | ALDH1A1 (0.51) | PTGIRPPARAPPARGPTGDR2ALDH1A1 | |
| SCHEMBL8356625 | 0.88 | PTGIR (0.56) | PTGIRPPARAPPARGPTGDR2ALDH1A1 | |
| SCHEMBL8356926 | 0.88 | ALDH1A1 (0.54) | PTGIRPPARAPPARGPTGDR2ALDH1A1 | |
| SCHEMBL8804289 | 0.82 | PTGDR2 (0.57) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL8356604 | 0.81 | PTGIR (0.60) | PTGIRPPARAPPARGPTGDR2KMT2A | |
| SCHEMBL8351416 | 0.81 | PTGIR (0.53) | PTGIRPPARAPPARGPTGDR2KMT2A | |
| SCHEMBL8803298 | 0.80 | PTGDR2 (0.60) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL9716964 | 0.80 | CNR1 (0.53) | PPARAPPARGSMN1; SMN2 | |
| SCHEMBL8358846 | 0.79 | PPARA (0.60) | PPARAPPARGALDH1A1HTTKMT2A | |
| SCHEMBL8354917 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |