Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230770 | 0.79 | GRIN1 (0.41) | GRIN1GRIN2AHRH1HTR2AALDH1A1 | |
| SCHEMBL9768636 | 0.77 | GRIN1 (0.70) | GRIN1GRIN2AHRH1HTR2ATAAR1 | |
| SCHEMBL5704251 | 0.77 | HRH1 (0.59) | HRH1HTR2ATAAR1SLC6A4SLC7A5 | |
| SCHEMBL10631765 | 0.75 | SLC7A5 (0.54) | HRH1HTR2ASLC6A4SLC7A5SLC6A2 | |
| SCHEMBL28769672 | 0.73 | GRIN1 (0.36) | GRIN1GRIN2AHRH1HTR2AALDH1A1 | |
| SCHEMBL2185597 | 0.73 | KDM4E (0.70) | GRIN1GRIN2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16935732 | 0.73 | GRIN1 (0.48) | GRIN1GRIN2AHRH1HTR2AALDH1A1 | |
| SCHEMBL2938035 | 0.71 | GRIN1 (0.71) | GRIN1GRIN2AHRH1HTR2ATAAR1 | |
| SCHEMBL11381473 | 0.70 | KDM4E (0.66) | GRIN1GRIN2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21896763 | 0.70 | KDM4E (0.66) | GRIN1GRIN2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543303-B1 | Hydrophilic hydrogels having a high swelling capacity | HOECHST AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| US-5331059-A | Absorbent materials, acrylic acid polymers crosslinked with diglycidyl phosphonates | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |
| EP-0543303-A1 | Hydrophilic hydrogels having a high swelling capacity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-26 | — | — | EP | disclosed |