SCHEMBL2185597

SCHEMBL2185597

NCCNCC(O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.70
L3MBTL1 Q9Y468 1/20 0.70
AOC3 Q16853 3/20 0.60
ALDH1A1 P00352 3/20 0.59
ADRB2 P07550 4/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
BCAT2 O15382 1/20 0.53
LMNA P02545 1/20 0.51
KMT2A Q03164 1/20 0.50
GRIN1 Q05586 2/20 0.48
GRIN2A Q12879 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11381473 0.96 KDM4E (0.66) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL21896763 0.96 KDM4E (0.66) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL20689722 0.86 KDM4E (0.73) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL7532494 0.83 KDM4E (1.00) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL4408535 0.83 KDM4E (1.00) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL5093264 0.83 KDM4E (0.52) KDM4EL3MBTL1AOC3ALDH1A1BCAT2
SCHEMBL6320068 0.82 KDM4E (0.73) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL1626455 0.82 KDM4E (0.73) KDM4EL3MBTL1AOC3ALDH1A1ADRB2
SCHEMBL9768636 0.82 GRIN1 (0.70) KDM4EL3MBTL1KMT2AGRIN1GRIN2A
SCHEMBL11747290 0.81 AOC3 (0.46) KDM4EL3MBTL1AOC3ALDH1A1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981958-B2 Oxazolidines derived from polyalkyl or polyalkenyl n-hydroxyalkyl succinimides, obtainment process and use INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-05-29 US disclosed
US-9221803-B2 Asphaltene-dispersing/inhibiting additive based on oxazolidines derived from polyalkyl or polyalkenyl N-hydroxyalkyl succinimides INSTITUTO MEXICANO DEL PETROLEO (MX) 2015-12-29 US disclosed
US-20110162558-A1 Formulations comprising an asphaltene-dispersing/inhibiting additive based on oxazolidines derived from polyalkyl or polyalkenyl N-hydroxyalkyl succinimides INSTITUTO MEXICANO DEL PETROLEO (MX) 2011-07-07 US disclosed
US-20100107478-A1 Oxazolidines derived from polyalkyl or polyalkenyl n-hydroxyalkyl succinimides, obtainment process and use INSTITUTO MEXICANO DEL PETROLEO (MX) 2010-05-06 US disclosed
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed
US-4117157-A TREATMENT OF CARDIOVASCULAR DISORDERS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-09-26 US disclosed
US-4005212-A ANTIDEPRESSANT, ANOREXIGENIC, PSYCHOENERGIZING, 2-PHENYL-2,3,5,6-TETRAHYDROIMIDAZO(2,1-B)THIAZOLE RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100107478-A1 Oxazolidines derived from polyalkyl or polyalkenyl n-hydroxyalkyl succinimides, obtainment process and use HRH4, OGDH, HRH3 KDM4E 338/4885L3MBTL1 2841/4885AOC3 43/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.