Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.60 |
| ▸ | ITGAV | P06756 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920936 | 0.95 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL8459316 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| Acetic Acid SCHEMBL8804256 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL7403069 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7483952 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL8804702 | 0.79 | F2 (0.37) | ITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL7489829 | 0.77 | ITGB3 (0.63) | ITGB3ITGA2BITGAV | |
| SCHEMBL7402090 | 0.77 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL7495244 | 0.75 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL7403276 | 0.74 | ITGB3 (0.55) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760658-A4 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0760658-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO. INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032710-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO., INC. (US) | 1995-12-07 | — | — | WO | disclosed |