SCHEMBL8805147

SCHEMBL8805147

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nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.47
ACE P12821 2/20 0.47
CPA1 P15085 1/20 0.47
ACE2 Q9BYF1 1/20 0.47
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40
PTGS2 P35354 1/20 0.40
THPO P40225 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
LTA4H P09960 3/20 0.39
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.37
ANPEP P15144 1/20 0.36
ECE1 P42892 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342125 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL21030512 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL8927997 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL291483 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL3373326 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL330009 0.90
SCHEMBL330011 0.90
SCHEMBL330308 0.90
SCHEMBL13253551 0.88 MME (0.40) MMEACECPA1ACE2ALDH1A1
SCHEMBL31631405 0.88 MME (0.40) MMEACECPA1ACE2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024613-B2 Composition containing a polymer and an additive École Polytechnique Fédérale De Lausanne (EPFL)—Technology Transfer Office (TTO) (CH) 2024-07-02 US disclosed
EP-3694921-A1 COMPOSITION CONTAINING A POLYMER AND AN ADDITIVE Ecole Polytechnique Fédérale de Lausanne (EPFL) EPFL-TTO (CH) 2020-08-19 EP disclosed
EP-0528955-B1 PROTEASE DEFICIENT BACTERIAL HOSTS GEN HOSPITAL CORP (US) 1997-08-13 EP disclosed
EP-0528955-A4 PROTEASE DEFICIENT BACTERIAL HOSTS 1993-06-16 EP disclosed
EP-0528955-A1 PROTEASE DEFICIENT BACTERIAL HOSTS. GEN HOSPITAL CORP (US) 1993-03-03 EP disclosed
US-5143846-A Escherichia Coli mutants THE GENERAL HOSPITAL CORPORATION (US) 1992-09-01 US disclosed
WO-1991017247-A1 PROTEASE DEFICIENT BACTERIAL HOSTS THE GENERAL HOSPITAL CORPORATION (US) 1991-11-14 WO disclosed