SCHEMBL291483

SCHEMBL291483

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nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.47
ACE P12821 2/20 0.47
CPA1 P15085 1/20 0.47
ACE2 Q9BYF1 1/20 0.47
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40
PTGS2 P35354 1/20 0.40
THPO P40225 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
LTA4H P09960 3/20 0.39
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.37
ANPEP P15144 1/20 0.36
ECE1 P42892 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342125 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL21030512 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL8805147 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL8927997 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL3373326 1.00 MME (0.47) MMEACECPA1ACE2ALDH1A1
SCHEMBL330009 0.90
SCHEMBL330011 0.90
SCHEMBL330308 0.90
SCHEMBL13253551 0.88 MME (0.40) MMEACECPA1ACE2ALDH1A1
SCHEMBL31631405 0.88 MME (0.40) MMEACECPA1ACE2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210023009-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY BEN GURION UNIV OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2021-01-28 US claimed
US-10842747-B2 Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery Ben-Gurion University of Negev R & D (IL) 2020-11-24 US claimed
EP-3539535-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY Ben-Gurion University of The Negev Research and Development Authority (IL) 2019-09-18 EP claimed
US-20180036376-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC (US) 2018-02-08 US claimed
US-20170367980-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY C/O BEN-GURION UNIV OF THE NEGEV R & D (IL) 2017-12-28 US claimed
US-20150246138-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC 2015-09-03 US claimed
US-20120164072-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2012-06-28 US claimed
EP-2427175-A2 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY Ben-gurion University Of The Negev Research And Development Authority (IL) 2012-03-14 EP claimed
WO-2010128504-A2 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2010-11-11 WO claimed
US-12448513-B2 Composition and method for the preparation of sheets, films, fibers, and molded parts ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) 2025-10-21 US disclosed
US-20240360179-A1 STAPLED PEPTIDES AND METHODS THEREOF PARABILIS MEDICINES, INC. 2024-10-31 US disclosed
CN-118307423-A Ionizable oligomer material, drug-loaded nano micelle containing ionizable oligomer material and application of drug-loaded nano micelle 华东师范大学 2024-07-09 CN disclosed
US-12024613-B2 Composition containing a polymer and an additive École Polytechnique Fédérale De Lausanne (EPFL)—Technology Transfer Office (TTO) (CH) 2024-07-02 US disclosed
CN-114096602-B Composition and method for preparing sheets, films, fibers and shaped parts 洛桑联邦理工学院 (EPFL) 2024-02-13 CN disclosed
US-20060039962-A1 Amphiphilic compounds and vesicles liposomes for organ-specified drug targeting BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2006-02-23 US disclosed
EP-1461014-A2 AMPHIPHILIC COMPOUNDS AND VESICLES/LIPOSOMES FOR ORGAN-SPECIFIC DRUG TARGETING Ben Gurion University Of The Negev Research And Development Authority (IL) 2004-09-29 EP disclosed
WO-2003047499-A2 AMPHIPHILIC COMPOUNDS AND VESICLES/LIPOSOMES FOR ORGAN-SPECIFIC DRUG TARGETING BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2003-06-12 WO disclosed
US-5665603-A REACTION WITH PHOSPHATE COMPOUND AND THIOCYANATE THE PERKIN-ELMER CORPORATION (US) 1997-09-09 US disclosed
WO-1995003066-A1 SELECTIVE MODIFICATION OF THE CARBOXY THERMINUS OF A PROTEIN PERKIN-ELMER CORPORATION (US) 1995-02-02 WO disclosed
EP-0441886-A1 EXPRESSION AND PROCESSING OF AUTHENTIC FGF'S IN YEAST. CHIRON CORP (US) 1991-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170367980-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY TSPO, ANXA6, ANXA11 MME 312/4885ACE 287/4885CPA1 469/4885
US-20120164072-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY TSPO, ANXA6, ANXA11 MME 312/4885ACE 287/4885CPA1 469/4885
US-20210023009-A1 NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY TSPO, ANXA6, ANXA11 MME 312/4885ACE 287/4885CPA1 469/4885
US-10842747-B2 Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery TSPO, ANXA6, ANXA11 MME 312/4885ACE 287/4885CPA1 469/4885
US-20150246138-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LGALS1, BOLA2; BOLA2B, LGALS2 MME 4006/4885ACE 2141/4885CPA1 831/4885
US-20240360179-A1 STAPLED PEPTIDES AND METHODS THEREOF CTNNB1, APC, CTNNA1 MME 479/4885ACE 898/4885CPA1 1057/4885
US-20060039962-A1 Amphiphilic compounds and vesicles liposomes for organ-specified drug targeting ABHD16A, CHMP4B, LIPG MME 212/4885ACE 385/4885CPA1 57/4885
US-20180036376-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LGALS1, BOLA2; BOLA2B, LGALS2 MME 4006/4885ACE 2141/4885CPA1 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.