Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218809 | 0.77 | POLB (0.41) | SMN1; SMN2L3MBTL1TP53POLBGAA | |
| SCHEMBL8804333 | 0.77 | ADORA1 (0.49) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL1918476 | 0.76 | ADORA1 (0.54) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL12532869 | 0.75 | RPS6KA3 (0.48) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL4362864 | 0.74 | ADORA1 (0.41) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL3199658 | 0.73 | ADORA1 (0.40) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL3209801 | 0.73 | HTT (0.41) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL5659777 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL5729868 | 0.72 | MAPT (0.51) | SMN1; SMN2ADORA3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL3220275 | 0.71 | ASIC3 (0.39) | MAPTKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645389-B1 | Process for the production of imidazopyridines | LONZA AG (CH) | 1997-02-05 | — | — | EP | disclosed |
| US-5446160-A | Process for preparing imidazopyridine derivatives | LONZA LTD. (CH) | 1995-08-29 | — | — | US | disclosed |
| EP-0645389-A1 | Process for the production of imidazopyridines | LONZA A.G. (CH) | 1995-03-29 | — | — | EP | disclosed |