Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085157 | 0.84 | PTGS2 (0.64) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL5698690 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL7085190 | 0.79 | PTGS2 (0.58) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL7084169 | 0.79 | PTGS2 (0.67) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL8805289 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL7084294 | 0.74 | PTGS2 (0.62) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL7090557 | 0.74 | PTGS2 (0.62) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL7083972 | 0.72 | PTGS2 (0.75) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL8802286 | 0.72 | PTGS2 (0.70) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 | |
| SCHEMBL7083925 | 0.71 | PTGS2 (0.73) | PTGS2PTGS1ALOX5ALDH1A1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | claimed |