Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914016 | 0.86 | CYP1A2 (0.38) | CYP1A2KDM4EKMT2A | |
| SCHEMBL6915421 | 0.74 | CYP1A2 (0.33) | CYP1A2KDM4EKMT2A | |
| SCHEMBL1282200 | 0.74 | KDM4E (0.37) | CYP1A2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL5750787 | 0.72 | KDM4E (0.35) | KDM4EKMT2A | |
| SCHEMBL7286601 | 0.72 | KDM4E (0.40) | CYP1A2KDM4EKMT2A | |
| SCHEMBL888643 | 0.68 | — | — | |
| SCHEMBL61405 | 0.67 | KDM4E (0.50) | KDM4EKMT2A | |
| SCHEMBL854175 | 0.67 | KDM4E (0.41) | CYP1A2KDM4EKMT2A | |
| SCHEMBL19035187 | 0.67 | CYP1A2 (0.37) | CYP1A2KDM4EKMT2A | |
| Piperazine SCHEMBL7553577 | 0.66 | TP53 (0.65) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433937-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433935-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433936-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2009027820-A2 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (DE) | 2009-03-05 | — | — | WO | disclosed |