Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647049 | 0.88 | CTSL (0.49) | LMNA | |
| SCHEMBL2417077 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2420021 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2370414 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2382050 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2370248 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2421029 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2382811 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL2416371 | 0.83 | NMBR (0.85) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL8804093 | 0.82 | SMN1; SMN2 (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746557-A4 | INTRACELLULAR SIGNALLING MEDIATORS | CELL THERAPEUTICS INC (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0746557-A1 | INTRACELLULAR SIGNALLING MEDIATORS | CELL THERAPEUTICS, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022546-A1 | INTRACELLULAR SIGNALLING MEDIATORS | CELL THERAPEUTICS, INC. (US) | 1995-08-24 | — | — | WO | disclosed |