Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 20/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 17/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852961 | 0.81 | OPRK1 (0.76) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL13221727 | 0.81 | OGFRL1 (0.68) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL853301 | 0.81 | OGFRL1 (0.80) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL853952 | 0.79 | OGFRL1 (0.80) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL852981 | 0.79 | OGFRL1 (1.00) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL13904385 | 0.78 | OGFRL1 (0.65) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL21548119 | 0.77 | OGFRL1 (0.59) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL17807902 | 0.77 | OGFRL1 (0.68) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL17807903 | 0.77 | OGFRL1 (0.68) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL19861178 | 0.76 | OGFRL1 (0.82) | OGFRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433935-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433937-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433936-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |