Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804023 | 0.87 | HTT (0.41) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8804215 | 0.87 | TRPV1 (0.40) | GAATRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8804979 | 0.85 | KMT2A (0.42) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8805159 | 0.82 | P2RY1 (0.41) | GAATRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8806812 | 0.82 | GAA (0.36) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8805313 | 0.82 | GAA (0.43) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8804222 | 0.81 | MCHR1 (0.39) | GAATRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8805284 | 0.79 | CFD (0.48) | GAATRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8804280 | 0.79 | CNR1 (0.51) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL8804953 | 0.78 | TRPV1 (0.49) | GAATRPV1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |