Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806779 | 0.94 | ABCG2 (0.67) | ABCB1ABCG2 | |
| SCHEMBL8809502 | 0.94 | ABCB1 (0.86) | ABCB1ABCG2 | |
| SCHEMBL8807182 | 0.94 | ABCB1 (0.66) | ABCB1ABCG2 | |
| SCHEMBL8807897 | 0.93 | ABCB1 (0.68) | ABCB1ABCG2 | |
| SCHEMBL8809137 | 0.93 | ABCG2 (0.70) | ABCB1ABCG2 | |
| SCHEMBL8806877 | 0.91 | ABCG2 (0.70) | ABCB1ABCG2 | |
| SCHEMBL8808324 | 0.88 | ABCB1 (0.65) | ABCB1ABCG2 | |
| SCHEMBL8808167 | 0.87 | ABCG2 (0.88) | ABCB1ABCG2 | |
| SCHEMBL8807475 | 0.87 | ABCG2 (0.63) | ABCB1ABCG2 | |
| SCHEMBL7168467 | 0.86 | ABCB1 (1.00) | ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |