SCHEMBL8807255

SCHEMBL8807255

C=CCc1ccc(-c2ccc(C(=O)O)cc2F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.59
ADH5 P11766 1/20 0.48
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
FOLH1 Q04609 1/20 0.43
MAPT P10636 3/20 0.42
ALOX5 P09917 2/20 0.40
MEN1 O00255 2/20 0.40
GAA P10253 2/20 0.40
GABRA1 P14867 2/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
GABRB2 P47870 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
GABRB1 P18505 1/20 0.40
RXRA P19793 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252810 0.81 RARB (0.61) RARBADH5ADRB1ADRB3FOLH1
SCHEMBL7778466 0.80 RARB (0.51) RARBMAPTMEN1KMT2ARXRA
SCHEMBL28548977 0.78 RARB (0.80) RARBADH5ADRB1ADRB3MAPT
SCHEMBL26572449 0.78 BCL2L1 (0.62) RARBADH5ADRB1ADRB3MEN1
Hydrochloric Acid SCHEMBL7777364 0.78 RARB (0.50) RARBMAPTMEN1KMT2ARXRA
Hydrochloric Acid SCHEMBL9332412 0.78 RARB (0.50) RARBMAPTMEN1KMT2ARXRA
SCHEMBL714706 0.78 ALDH1A1 (0.54) MAPTMEN1GAAKMT2APOLB
SCHEMBL29473809 0.76 RARB (0.56) RARBADH5MAPTMEN1KMT2A
SCHEMBL2041007 0.76 RARB (0.56) RARBADH5MAPTMEN1KMT2A
SCHEMBL14691493 0.76 ALDH1A1 (0.52) MAPTMEN1GAAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9012509-A None JP disclosed
JP-H0912509-A ANTIFERROELECTRIC LIQUID CRYSTAL COMPOUND AND ITS COMPOSITION SHOWA SHELL SEKIYU KK 1997-01-14 JP disclosed