Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7286588 | 0.85 | SMYD3 (0.50) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL8805370 | 0.81 | SLC6A4 (0.53) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL7274510 | 0.81 | CRBN (0.53) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| Hydrochloric Acid SCHEMBL7287777 | 0.81 | CRBN (0.48) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL7295942 | 0.80 | PDE3B (0.50) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| Bromide SCHEMBL11199816 | 0.80 | CRBN (0.52) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL11196268 | 0.80 | CRBN (0.52) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL7295933 | 0.79 | CRBN (0.54) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL11194801 | 0.78 | SLC6A4 (0.64) | SLC6A4PDE3BPDE3AKCNH2NR3C1 | |
| SCHEMBL7269908 | 0.76 | SLC6A4 (0.78) | SLC6A4PDE3BPDE3AKCNH2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583136-B1 | Piperidino-3,4-dihydrocarbostyryl compounds for the treatment of ischemic disorders | KISSEI PHARMACEUTICAL (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5294718-A | Platelet aggregation inhibitors; antiischemic agents; side effect reduction | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0583136-A2 | Piperidino-3,4-dihydrocarbostyryl compounds for the treatment of ischemic disorders | Kissei Pharmaceutical Co., Ltd. (JP) | 1994-02-16 | — | — | EP | disclosed |