Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983663 | 0.83 | MEN1 (0.58) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL2303474 | 0.83 | MEN1 (0.58) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL18547701 | 0.81 | KMT2A (0.56) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL69791 | 0.78 | HTT (0.69) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL28655251 | 0.78 | CYP2C19 (0.56) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL6440734 | 0.78 | MEN1 (0.56) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL17582660 | 0.78 | MEN1 (0.56) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL24479152 | 0.77 | ALDH1A1 (0.54) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL28582917 | 0.77 | MEN1 (0.51) | CYP2C19MEN1CYP1A2KMT2AHTT | |
| SCHEMBL21592078 | 0.76 | MEN1 (0.54) | CYP2C19MEN1CYP1A2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320628-B1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5112848-A | Antiasthmatics and antiarthritic agents | ABBOTT LABORATORIES (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |