Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811512 | 0.83 | NTRK1 (0.45) | ALDH1A1MAPTGAAKDM4EGLA | |
| SCHEMBL15729888 | 0.81 | NTRK1 (0.56) | ALDH1A1MAPTGAAKDM4EGLA | |
| SCHEMBL8811614 | 0.79 | POLB (0.46) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL6284260 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL6280609 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAKDM4ETRPV1 | |
| SCHEMBL59718 | 0.74 | GRM5 (0.62) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL7209828 | 0.72 | KMT2A (0.54) | ALDH1A1MAPTGAAKDM4EGLA | |
| SCHEMBL11076373 | 0.72 | KMT2A (0.58) | ALDH1A1MAPTGAAKDM4EGLA | |
| SCHEMBL8177930 | 0.72 | KMT2A (0.71) | ALDH1A1MAPTGAAKDM4EGLA | |
| SCHEMBL28611324 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |